Liver Fibrosis Clinical Trials
After Grace’s Liver Biopsy and post sedation delirium which I have developed a significant distaste for some of these research efforts are of great appeal. Not to mention many other aspects of a hospital stay.
This was the attempt post biopsy to keep an IV.
There are currently over 900 studies listed related to Liver Fibrosis; I only scrolled through the first 200.
Official Title:
Noninvasive Stage Identification of Hepatic Fibrosis Using 4D-MRI
Actual Study Start Date :
August 1, 2021
Estimated Primary Completion Date :
June 30, 2024
Estimated Study Completion Date :
December 31, 2024
“This research project proposes a novel MR-based quantitative Liver Deformation Biomarker (qLDB) approach for non-invasive liver fibrosis assessment by using a new technique called 4D-MRI. This technique makes it possible to overcome limitations in currently used techniques, i.e. to capture the abdominal organs with high spatial resolution in 3-dimensions at a high frame rate of 2-3 Hz and enabled an entirely new insight into the human body. The final diagnosis (i.e., stage of fibrosis) is based on quantifying changes of the liver's mechanical properties by dynamic magnetic resonance (MR) measurements and comparing the liver's elastic deformation with healthy livers. This innovative methodology allows for the first time to quantitatively measure the elastic deformation of organs during free-breathing and for an extended period, since no harmful X-rays are required. The hypothesis of the study is that the mechanical changes a liver undergoes during liver disease progression are visible in 4D-MRI data sets as a reduced elasticity.”
https://www.clinicaltrials.gov/ct2/show/NCT05385237?cond=Liver+Fibrosis&draw=4&rank=203
Official Title:
The Effects of Sildenafil for Liver Fibrosis in Adolescents and Adults After Fontan Operation: An Open-label, Randomized Controlled, Pilot Trial.
Actual Study Start Date :
July 3, 2017
Estimated Primary Completion Date :
July 1, 2023
Estimated Study Completion Date :
December 31, 2023
https://www.clinicaltrials.gov/ct2/show/NCT04908657?cond=Liver+Fibrosis&draw=4&rank=3
Official Title:
Development of Novel MRI Methods for Detecting, Discriminating, and Measuring Liver Fibrosis and Congestion in Fontan Patients
Actual Study Start Date :
May 9, 2018
Estimated Primary Completion Date :
April 2023
Estimated Study Completion Date :
April 2023
https://www.clinicaltrials.gov/ct2/show/NCT03539757?cond=Liver+Fibrosis&draw=4&rank=4
Official Title:
Relationship Between the Development of Impaired Glucose Tolerance, the Phenotype of CFLD, and the Risk of Liver Fibrosis
Actual Study Start Date :
March 31, 2022
Estimated Primary Completion Date :
June 2023
Estimated Study Completion Date :
December 2023
https://www.clinicaltrials.gov/ct2/show/NCT05229640?cond=Liver+Fibrosis&draw=11&rank=76
Official Title:
Competitive Accuracy of Radiological Imaging Compared to Liver Biopsy in Patients With Liver Fibrosis
Actual Study Start Date :
August 1, 2018
Actual Primary Completion Date :
January 31, 2020
Actual Study Completion Date :
January 31, 2020
https://www.clinicaltrials.gov/ct2/show/NCT05008263?cond=Liver+Fibrosis&draw=6&rank=26
Official Title:
Liquid Biopsy as a Non-invasive Tool for the Diagnosis of NASH and Liver Fibrosis
Actual Study Start Date :
December 16, 2020
Actual Primary Completion Date :
March 16, 2021
Actual Study Completion Date :
April 16, 2021
https://www.clinicaltrials.gov/ct2/show/NCT04677101?cond=Liver+Fibrosis&draw=7&rank=32
Official Title:
Shear Wave Sonoelastography for the Noninvasive Evaluation of Hepatic Fibrosis in the Pediatric Population
Actual Study Start Date :
May 11, 2015
Actual Primary Completion Date :
May 31, 2018
Actual Study Completion Date :
May 31, 2018
https://www.clinicaltrials.gov/ct2/show/NCT02372682?cond=Liver+Fibrosis&draw=14&rank=110
Official Title:
Beyond Confounders: Addressing Source of Measurement Variability and Error in Shear Wave Elastography
Actual Study Start Date :
June 29, 2017
Actual Primary Completion Date :
August 14, 2018
Actual Study Completion Date :
August 30, 2018
https://www.clinicaltrials.gov/ct2/show/NCT03342560?cond=Liver+Fibrosis&draw=4&rank=131
Official Title:
Prospective Detection of Liver Fibrosis With MRI Compared to Fibroscan and Blood Tests
Study Start Date :
October 2010
Actual Primary Completion Date :
July 31, 2017
Actual Study Completion Date :
July 31, 2017
https://www.clinicaltrials.gov/ct2/show/NCT01600105?cond=Liver+Fibrosis&draw=14&rank=101